Ceruloplasmin Deficiency Impaired Brain Iron Metabolism and Behavior in Mice

February 21, 2022 0 Comments

Iron accumulation is an important cause of various brain diseases. As a ferroxidase, ceruloplasmin (Cp) plays a key role in iron homeostasis and its abnormal activity leads to iron accumulation. However, the detailed biological function of Cp in brain iron homeostasis needs to be investigated. In this study, Cp knockout mice were prepared and the …